Under-reporting bipolar disorder in large-scale epidemiologic studies

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dc.contributor.affiliationInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, Saint George Hospital University Medical Center, Balamand University, Faculty of Medicine, Beirut, Lebanon
dc.contributor.emailegkaram@idraac.org (E.G. Karam)
dc.creatorKaram, Elie G.es_ES
dc.creatorSampson, Nancyes_ES
dc.creatorItani, Lynnes_ES
dc.creatorAndrade, Laura Helenaes_ES
dc.creatorBorges, Guilhermees_ES
dc.creatorChiu, Wai Tates_ES
dc.creatorFlorescu, Silviaes_ES
dc.creatorHoriguchi, Itsukoes_ES
dc.creatorZarkov, Zaharies_ES
dc.creatorAkiskal, Hagopes_ES
dc.date2014
dc.date.accessioned2025-08-29T19:41:03Z
dc.date.accessioned2026-03-27T15:32:23Z
dc.date.available2025-08-29T19:41:03Z
dc.date.issued2014
dc.date.published2014
dc.descriptionBackground: To investigate if the prevalence of bipolar disorder in epidemiologic studies is an underestimate, as suggested by clinical studies. Methods: We analyzed data from 8 countries that participated in the World Mental Health Survey Initiative (n=47,552). We identified 6.8% and 18.9% of the sample who we think were screened out inappropriately (SCI) from the euphoric and irritable bipolar sections respectively. We compared them to those who were allowed to continue the section (CONT, 2.6% of the sample for euphoric; 1.0% for irritable) and to the reference group (REF, 69.5% of the sample). Results: The SCI group had consistently higher rates of major depression (29.1% vs. 6.4%), earlier age of onset (24.3y vs. 32.4y), more suicide attempts (13.3% vs. 5.9%), and more episodes (4.2 vs. 2.7) than the REF for the euphoric group. Similar findings exist for the irritable group. Also, comorbidity with anxiety, disruptive behavior disorders and substance use were much higher than the REF. Limitations: As with all epidemiologic studies, recall bias cannot be ruled out. Conclusions: The findings above suggest that a number of the SCI subjects belong to the bipolar group. A revision of instruments used in epidemiologic research will probably prove what clinical studies have been showing that bipolar disorder is more common than has been reported.es_ES
dc.formatPDFes_ES
dc.identifier.doi10.1016/j.jad.2014.01.011
dc.identifier.eissn1573-2517
dc.identifier.issn0165-0327
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.placePaíses Bajos
dc.identifier.urihttps://doi.org/10.1016/j.jad.2014.01.011
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/8392
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relation159:147-54
dc.relation.jnabreviadoJ AFFECT DISORD
dc.relation.journalJournal of Affective Disorders
dc.rightsAcceso Cerradoes_ES
dc.subject.kwBipolar disorder
dc.subject.kwDiagnosis
dc.subject.kwComposite International
dc.subject.kwDiagnostic Interview
dc.titleUnder-reporting bipolar disorder in large-scale epidemiologic studieses_ES
dc.typeArtículoes_ES

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